The Estée Lauder Companies has taken an undisclosed minority stake in 111SKIN, the luxury clinical skincare brand founded by plastic and reconstructive surgeon Dr. Yannis Alexandrides. Terms of the deal were not disclosed.
Founded in 2012, 111SKIN was originally developed by Dr. Alexandrides as post-procedure skincare for his own surgical patients. Its anchor formulation, NAC Y2™, is positioned around skin repair and barrier resilience. The brand's portfolio now spans more than 30 SKUs across the Black Diamond and Reparative collections, priced from $50 to $1,000.
A brand built on luxury retail and DTC
111SKIN has built a diversified global footprint: North America accounts for roughly 40% of 2025 sales, with active presence in the UK, Europe, China, and Asia Pacific.
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Its retail distribution skews high-end (Harrods, Bluemercury, Nordstrom, Mandarin Oriental, and Aman), and direct-to-consumer represents around 20% of revenue.
"Skin care is entering a new phase, shaped by the convergence of procedures, longevity and beauty," said Stéphane de La Faverie, President and CEO of The Estée Lauder Companies.
"111SKIN exemplifies this shift, translating Dr. Alexandrides' more than 35 years of surgical and aesthetic treatment experience into high-performance luxury skin care," adds Stéphane.
Dr. Yannis and Eva Alexandrides remain co-founders and active in the business, while CEO Vanessa Goddevrind continues to lead day-to-day operations.
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